Motherwell's Conference League journey is over after a rampant Freiburg side overwhelmed them 4-1 in Germany in their play-off second leg.
Trailing last season's Europa League finalists 3-1 on aggregate, Alfred Johansson's men had an almighty task to qualify for the league phase, after coming through two rounds of qualifiers to reach this stage.
And the visitors were further behind in the opening five minutes.
Winger Derry Scherhant burst in behind to latch onto a smart through ball, opened up his body, and curled it past the onrushing Alex Paulsen.
Not to be deterred, Motherwell levelled on the night after a speculative Emmanuel Longelo strike from 30 yards was inexplicably spilled into his own net by goalkeeper Mio Backhaus.
However, Motherwell fell by the wayside in the second half after Jake Girdwood-Reich was shown a straight red card for a lunging challenge.
In the next six minutes, Freiburg scored two headers from inswinging corners, first through striker Igor Matanovic, followed by Cyriaque Irie glancing in.
The Bundesliga side remained relentless, hitting the bar, a post, and having a shot cleared off the line in the space of 60 seconds, and a powerful Maximilian Eggestein effort was well saved.
And the tie was finished when Keisuke Goto was left unmarked in the middle of the box and crashed in a late fourth for the visitors.